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Comparisons of neurodegeneration over time between healthy ageing and Alzheimer's disease cohorts via Bayesian inference.

Marcela I CespedesJurgen FrippJames M McGreeChristopher C DrovandiKerrie MengersenJames D Doecke
Published in: BMJ open (2017)
To the best of our knowledge, this is the first application of Bayesian LME models to neuroimaging data which provides inference on a population and individual level in the AD field. The application of a Bayesian LME framework allows for additional information to be extracted from longitudinal studies. This provides health professionals with valuable information of neurodegeneration stages, and a potential to provide a better understanding of disease pathology.
Keyphrases
  • healthcare
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  • risk assessment
  • data analysis
  • deep learning
  • mild cognitive impairment