To what extent does prior antimicrobial therapy affect the diagnostic performance of radiolabeled leukocyte scintigraphy in infective endocarditis?
Katarzyna HolcmanPaweł RubiśBogdan ĆmielAndrzej ZąbekKrzysztof BoczarWojciech SzotZuzanna KalarusKatarzyna GraczykMaksymilian HanarzBarbara MałeckaPiotr PodolecMagdalena KostkiewiczPublished in: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology (2022)
Prior antibiotic therapy affects 99mTc-HMPAO-SPECT/CT diagnostic properties. Patients treated with antimicrobial therapy display false-negative 99mTc-HMPAO-SPECT/CT results more often, especially if intravenous, definite, or combination regimens are administered.