A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients.
Akshita GuptaAjay KumarAsem Ali AshrafHaritha MadigubbaKiran ChawlaPublished in: Tropical doctor (2020)
There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.
Keyphrases
- hiv aids
- pulmonary tuberculosis
- antiretroviral therapy
- high throughput
- mycobacterium tuberculosis
- human immunodeficiency virus
- hiv infected
- hiv positive
- end stage renal disease
- ejection fraction
- single molecule
- emergency department
- prognostic factors
- chronic kidney disease
- hepatitis c virus
- high resolution
- risk factors
- single cell
- high speed
- drug induced