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Cluster oligonucleotide signatures for rapid identification by sequencing.

Manuel ZaharievWen ChenCobus M VisagieC André Lévesque
Published in: BMC bioinformatics (2018)
Cluster signatures provide a rapid and universal analysis tool to identify all possible short diagnostic DNA markers and variants from any DNA sequencing dataset. They are particularly useful in discriminating genetic material from closely related organisms and in detecting deleterious mutations in highly or perfectly conserved genomic sites.
Keyphrases
  • copy number
  • genome wide
  • circulating tumor
  • cell free
  • single cell
  • single molecule
  • loop mediated isothermal amplification
  • dna methylation
  • transcription factor
  • circulating tumor cells
  • sensitive detection