Mutual effect of cerebral amyloid β and peripheral lymphocytes in cognitively normal older individuals.

Fumihiko YasunoHiroaki KazuiKatsufumi KajimotoMasafumi IharaNaomi MoritaAkihiko TaguchiAkihide YamamotoKiwamu MatsuokaMasato TakahashiJyoji NakagawaraMasahito TsujiHidehiro IidaToshifumi KishimotoKazuyuki Nagatsuka

Published in: International journal of geriatric psychiatry (2017)

Our results indicated that a specific peripheral immune response, reflected in the increased ratio of cytotoxic T cells, could be regarded as a preclinical sign of AD and could be attributed to the Aβ neuropathological mechanism. Copyright © 2017 John Wiley & Sons, Ltd.

Keyphrases

immune response
chemotherapy induced
subarachnoid hemorrhage
cognitive decline
peripheral blood
physical activity
middle aged
cell therapy
mild cognitive impairment
stem cells
cerebral ischemia
brain injury
bone marrow