A model of porcine polymicrobial septic shock.

Finnja Marie Zurek-LeffersFlorian LehmannLaura BrabenecSebastian KintrupKatharina E M HellenthalKira MersjannFelicia KneifelMichael HesslerPhilip-Helge ArnemannTim-Gerald KampmeierChristian ErtmerPatrick KellnerNana-Maria Wagner

Published in: Intensive care medicine experimental (2023)

We here established a model of septic shock in pigs that meets the clinical criteria of septic shock utilized in human patients. Our model may thus serve as a reference for clinically relevant sepsis research in pigs.

Keyphrases

septic shock
end stage renal disease
endothelial cells
chronic kidney disease
newly diagnosed
induced pluripotent stem cells