Cisplatin-induced PANDAR-Chemo-EVs contribute to a more aggressive and chemoresistant ovarian cancer phenotype through the SRSF9-SIRT4/SIRT6 axis.

Peiling Li Yinuo Li Yanan Wang Xiumin Shang Zhongxin Yan Shengli Li Wei Bao

Published in: Journal of gynecologic oncology (2023)

Cisplatin-induced exosomes transfer PANDAR and lead to a rapid adaptation of OC cell survival through accumulating SRSF9 following cisplatin stress exposure.

Keyphrases

oxidative stress
ischemia reperfusion injury
mesenchymal stem cells
photodynamic therapy
stem cells
combination therapy
loop mediated isothermal amplification
locally advanced
stress induced
drug delivery
radiation therapy
sensitive detection