Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media.
Nanno F A W PeekMarja J NellRonald BrandThekla Jansen-WerkhovenEwoud J van HoogdalemRuud VerrijkMarcel J VonkAmon R WafelmanA Rob P M ValentijnJohan H M FrijnsPieter S HiemstraJan W DrijfhoutPeter H NibberingJan J GrotePublished in: PloS one (2020)
The efficacy/safety balance assessed in the present study provides a compelling justification for continued clinical development of P60.4Ac in therapy-resistant CSOM.
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