Relation of Testosterone, Dihydrotestosterone, and Estradiol With Changes in Outcomes Measures in the Testosterone Trials.

Alisa J Stephens-ShieldsPeter J SnyderSusan S EllenbergLynne TaylorShalender Bhasin

Published in: The Journal of clinical endocrinology and metabolism (2022)

Change in estradiol level was the best predictor not only of the change in vBMD and sexual desire but also of the changes in hemoglobin and HDL cholesterol. Consideration of testosterone, estradiol, and DHT together offers a superior prediction of treatment response in older hypogonadal men than testosterone alone.

Keyphrases

replacement therapy
smoking cessation
estrogen receptor
middle aged
type diabetes
adipose tissue
red blood cell