Ginger (Zingiber Officinale)-derived nanoparticles in Schistosoma mansoni infected mice: Hepatoprotective and enhancer of etiological treatment.

Wegdan M Abd El Wahab Ayman A El-BadrySoheir S MahmoudYaser A El-Badry Mohamed A El-Badry Doaa Ahmed Hamdy

Published in: PLoS neglected tropical diseases (2021)

GNPs have a schistosomicidal, antioxidant, and hepatoprotective role. GNPs have a strong synergistic effect when combined with etiological treatments (PZQ or MFQ), and significantly reduced therapeutic doses by 50%, which may mitigate side effects and resistance to etiological drugs, a hypothesis requiring further research. We recommend extending this study to humans.

Keyphrases

oxidative stress
transcription factor
high fat diet induced
metabolic syndrome
skeletal muscle
insulin resistance
walled carbon nanotubes