Endothelin-1 is associated with mortality that can be attenuated with high intensity statin therapy in patients with stable coronary artery disease.

Ruizhu LinJuhani JunttilaJarkko PiuholaE Samuli LepojärviJohanna MaggaAntti M KiviniemiJuha PerkiömäkiHeikki HuikuriOlavi UkkolaMikko TulppoRisto Kerkelä

Published in: Communications medicine (2023)

Our data suggests a prognostic value for high circulating ET-1 in patients with stable CAD. High intensity statin therapy associates with reduction of risk for all-cause mortality and CV death in CAD patients with high ET-1.

Keyphrases

high intensity
coronary artery disease
cardiovascular events
resistance training
percutaneous coronary intervention
cardiovascular disease
coronary artery bypass grafting
stem cells
risk factors
aortic stenosis
deep learning
acute coronary syndrome
data analysis
mesenchymal stem cells