Oligogenic inheritance in severe adult obesity.
Sumaya AlmansooriSuzanne I AlstersAndrianos M YiorkasNikman Adli Nor HashimRobin G WaltersHarvinder S ChahalSanjay PurkayasthaNader G LessanAlexandra I F BlakemorePublished in: International journal of obesity (2005) (2024)
Oligogenic inheritance may explain some of the variable penetrance in Mendelian forms of obesity. We caution clinicians and researchers to avoid confining sequence analysis to individual genes and, in particular, not to stop looking when the first potentially-causative mutation is found.