A wearable cardiac ultrasound imager.
Hongjie HuHao HuangMohan LiXiaoxiang GaoLu YinRuixiang QiRay S WuXiangjun ChenYuxiang MaKeren ShiChenghai LiTimothy M MausBrady HuangChengchangfeng LuMuyang LinSai ZhouZhiyuan LouYue GuYimu ChenYusheng LeiXinyu WangRuotao WangWentong YueXinyi YangYizhou BianJing MuGeonho ParkShu XiangShengqiang CaiPaul W CoreyJoseph WangSheng XuPublished in: Nature (2023)
Continuous imaging of cardiac functions is highly desirable for the assessment of long-term cardiovascular health, detection of acute cardiac dysfunction and clinical management of critically ill or surgical patients 1-4 . However, conventional non-invasive approaches to image the cardiac function cannot provide continuous measurements owing to device bulkiness 5-11 , and existing wearable cardiac devices can only capture signals on the skin 12-16 . Here we report a wearable ultrasonic device for continuous, real-time and direct cardiac function assessment. We introduce innovations in device design and material fabrication that improve the mechanical coupling between the device and human skin, allowing the left ventricle to be examined from different views during motion. We also develop a deep learning model that automatically extracts the left ventricular volume from the continuous image recording, yielding waveforms of key cardiac performance indices such as stroke volume, cardiac output and ejection fraction. This technology enables dynamic wearable monitoring of cardiac performance with substantially improved accuracy in various environments.
Keyphrases
- left ventricular
- deep learning
- ejection fraction
- aortic stenosis
- heart rate
- mitral valve
- acute myocardial infarction
- machine learning
- high resolution
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- acute coronary syndrome
- coronary artery
- atrial fibrillation
- brain injury
- hepatitis b virus
- aortic valve
- blood brain barrier
- percutaneous coronary intervention
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome