FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells.

Tomeka L SuberIna NikolliMichael E O'BrienJames LondinoJing ZhaoKong ChenRama K MallampalliYutong Zhao

Published in: Respiratory research (2018)

These data support a role for FBXO17 abundance, when left unchecked, in regulating cell proliferation and survival through modulation of Akt and ERK kinase activation. The data raise a potential role for the F-box subunit in modulating tumorigenesis.

Keyphrases

cell proliferation
signaling pathway
pi k akt
induced apoptosis
cell cycle
cell cycle arrest
electronic health record
big data
protein kinase
tyrosine kinase
oxidative stress
data analysis
cell death
free survival