Brain structural abnormalities in the preclinical stage of Machado-Joseph disease/spinocerebellar ataxia type 3 (MJD/SCA3): evaluation by MRI morphometry, diffusion tensor imaging and neurite orientation dispersion and density imaging.
Mengcheng LiXinyuan ChenHao-Ling XuZiqiang HuangNaping ChenYuqing TuShirui GanJianping HuPublished in: Journal of neurology (2021)
NOODI can provide novel quantitative microstructural changes in MJD/SCA3 carriers, expanding our understanding of the gray and white matter (axons and dendrites) degeneration in this frequent ataxia syndrome.