A Randomized, Open-Label, Two-Treatment Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of Diazepam Nasal Spray in Healthy Adult Subjects.

This study in healthy volunteers demonstrated that food significantly decreases and delays the absorption of diazepam dosed via nasal spray. Patients using diazepam nasal spray after eating may obtain diazepam concentrations that are below those needed for seizure control.