Retinitis Pigmentosa (RP): The Role of Oxidative Stress in the Degenerative Process Progression.
Enzo Maria VingoloLorenzo CasilloLaura ContentoFrancesca TojaAntonio FloridoPublished in: Biomedicines (2022)
Our findings suggest that oxidative stress may speed cone photoreceptors' morphological damage (CMT); because long lasting oxidative stress in the RP may cause oxidative damage, with animal models of RP suggesting this is a micromolecular mechanism of photoreceptors' (cone) death, it can be similar to cone damage in human RP eyes. The limitations of this paper are the relatively small sample, the horizontal design of the study, and the lack of data about the levels of ROS in the vitreous body.