Glutamatergic neurotransmission in schizophrenia: A systematic review and quantitative synthesis of proton magnetic resonance spectroscopy studies across schizophrenia spectrum disorders.

Jamie J Lopes Sean P Carruthers Denny MeyerBrian DeanSusan Lee Rossell

Published in: The Australian and New Zealand journal of psychiatry (2024)

The review highlights abnormal glutamatergic metabolite levels throughout schizophrenia spectrum disorders and in specific brain regions. The review underscores the importance of standardized future research assessing glutamatergic metabolites using proton magnetic resonance spectroscopy due to considerable literature heterogeneity.

Keyphrases

bipolar disorder
systematic review
white matter
single cell
resting state
mass spectrometry
case control