Isolation of Secretome with Enhanced Antifibrotic Properties from miR-214-Transfected Adipose-Derived Stem Cells.

Jung Hyun Park Ok-Hee Kim Kee-Hwan Kim Ha-Eun Hong Haeyeon Seo Ho Joong Choi Joseph Ahn Tae Yoon Lee Say June Kim

Published in: Journal of Korean medical science (2019)

MicroRNA-214 transfection stimulates ASCs to release the secretome with higher antifibrotic and anti-inflammatory properties. miR-214-secretome is thus expected to be one of the prominent ways of overcoming liver fibrosis, if further studies consistently validate its safety and efficiency.

Keyphrases

liver fibrosis
cell proliferation
long non coding rna
long noncoding rna
anti inflammatory
pulmonary fibrosis
case control