Cluster analysis of 100 Marfan patients based on aortic 4D flow MRI and Z-score: insights into disease heterogeneity and stratification of subgroups.

Alexander LenzFlora BahrChristoph RiedelFelicia WrightMartin SinnShuo ZhangMarion SchuettLennart WellGerhard AdamYskert von KodolitschBjoern P SchoennagelPeter Bannas

Published in: European radiology (2024)

Four-dimensional (4D) flow MRI-derived variables of Marfan patients are highly heterogeneous across varying Z-scores. Cluster analysis based on 4D flow MRI and Z-score revealed three distinct subgroups of Marfan patients. A combination of Z-score and 4D flow MRI-derived parameters may identify different stages of aortic disease in Marfan patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
magnetic resonance imaging
prognostic factors
peritoneal dialysis
heart failure
computed tomography
coronary artery
pulmonary arterial hypertension