Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease.
Maria Sabater MolinaElisa Nicolás RocamoraAsunción Iborra BendichoElisa García VázquezEsther ZorioFernando Domínguez RodriguezCristina Gil OrtuñoAna Isabel RodríguezAntonio J Sánchez-LópezRubén Jara RubioAntonio Moreno-DocónPedro J MarcosPablo García PavíaRoberto Barriales VillaJuan R Gimeno BlanesPublished in: PloS one (2022)
Different genetic variants in ACE2 were associated with a severe clinical course and death groups of patients with COVID-19. ACE2 common SNPs in the population might modulate severity of COVID-19 infection independently of other known markers like gender, age and comorbidities.