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The D allele of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism is associated with worse functional outcome of ischaemic stroke.

Rusdy Ghazali MaluekaEry Kus DwianingsihSri SutarniRheza Gandi BawonoHalwan Fuad BayuanggaAbdul GofirIsmail Setyopranoto
Published in: The International journal of neuroscience (2017)
This study showed that the D allele in ACE I/D polymorphism is associated with worse functional outcomes. This highlights the possibility of further research to improve functional outcomes of ischaemic stroke by inhibiting the ACE system.
Keyphrases
  • angiotensin converting enzyme
  • angiotensin ii
  • signaling pathway