Emergence of a novel ISS1N-optrA-carrying transposon within an integrative and conjugative element from Streptococcus parasuis.
Xingyang DaiJunjie SunWenbin ZhaoJianzhong WangXiaohui ZhangXiao LiuAijuan LiJiaqi ZhaoPeizhao HanXiaoming WangLiping WangJinhu HuangPublished in: The Journal of antimicrobial chemotherapy (2023)
ISS1N was found to be associated with optrA spreading for the first time. Integration of the ISS1N-optrA transposon within ICESpsuSFJ45 may lead to the co-selection of optrA with other antimicrobial resistance genes, contributing to its horizontal transfer from S. parasuis to clinically more important bacterial pathogens.