Assessing the Associations of Growth Differentiation Factor 15 with Rheumatic Diseases Using Genetic Data.

Ding YeBin LiuZhixing HeLin HuangYu QianKeding ShaoChengping WenYingying Mao

Published in: Clinical epidemiology (2021)

Our study suggested an inverse association between circulating GDF-15 levels and risk of SLE, and further studies are warranted to elucidate the underlying biological mechanisms. There was limited evidence supporting a causal association of circulating GDF-15 levels with risk of RA and IBD.

Keyphrases

systemic lupus erythematosus
disease activity
rheumatoid arthritis
electronic health record
genome wide
big data
machine learning
dna methylation
artificial intelligence