Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activation: a translational study.
Yufei ChenWanrong FuYunbo ZhengJing YangYangyang LiuZhiyong QiMeiling WuZhichao FanKanhua YinYunfeng ChenWen GaoZhongren DingChunguang QiuQi LiSi ZhangLiang HuPublished in: European heart journal (2022)
Galectin-3 is a novel positive regulator of platelet hyperreactivity and thrombus formation in CAD. As TD139 has potent antithrombotic effects without bleeding risk, Galectin-3 inhibitors may have therapeutic advantages as potential antiplatelet drugs for patients with high plasma Galectin-3 levels.