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Assessment of stromal tumor infiltrating lymphocytes and immunohistochemical features in invasive micropapillary breast carcinoma with long-term outcomes.

Frederik DemanKevin PunieAnnouschka LaenenPatrick NevenEva OldenburgerAnn SmeetsInes NevelsteenChantal Van OngevalAdinda BatenTimothy FaesMelissa ChristiaensHilde JanssenCaroline WeltensChristine DesmedtHans WildiersGiuseppe Floris
Published in: Breast cancer research and treatment (2020)
Clinicopathological features, geographical distribution of sTILs and TAPC are similar between pure and non-pure IMPCs. Despite a high proportion of grade 3 tumors and lymph node involvement, we observed a low rate of distant recurrences and breast cancer-related death in this cohort of stage I-III IMPCs treated with primary surgery. Caution in interpretation of the observed prognostic correlations is required given the very low number of events, warranting validation in other cohorts.
Keyphrases
  • lymph node
  • minimally invasive
  • bone marrow
  • neoadjuvant chemotherapy
  • coronary artery bypass
  • sentinel lymph node
  • peripheral blood
  • radiation therapy
  • newly diagnosed
  • locally advanced
  • clinical evaluation
  • rectal cancer