Lleida Bat Lyssavirus isolation in Miniopterus schreibersii in France.

Evelyne Picard-MeyerVeronique BevenEdouard HirchaudCédric GuillaumeGérald LarcherEmmanuelle Robardet Alexandre ServatYannick BlanchardFlorence Cliquet

Published in: Zoonoses and public health (2018)

Bat rabies cases are attributed in Europe to five different Lyssavirus species of 16 recognized Lyssavirus species causing rabies. One of the most genetically divergent Lyssavirus spp. has been detected in a dead Miniopterus schreibersii bat in France. Brain samples were found positive for the presence of antigen, infectious virus and viral RNA by classical virological methods and molecular methods respectively. The complete genome sequence was determined by next-generation sequencing. The analysis of the complete genome sequence confirmed the presence of Lleida bat lyssavirus (LLEBV) in bats in France with 99.7% of nucleotide identity with the Spanish LLEBV strain (KY006983).

Keyphrases

genome wide
sars cov
gene expression
white matter
hiv infected
copy number
amino acid
antiretroviral therapy
multiple sclerosis
dna methylation
hiv infected patients
single molecule