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Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes.

Jean-Baptiste PingaultAndrea G AllegriniTracy OdigieLeonard FrachJessie R BaldwinFrühling Vesta RijsdijkFrank Dudbridge
Published in: Journal of child psychology and psychiatry, and allied disciplines (2022)
Strikingly, using polygenic scores may, in some cases, lead to more bias than not using them. Appropriately conducting and interpreting polygenic score studies thus requires researchers in child psychology and psychiatry and beyond to be versed in both epidemiological and genetic methods or build on interdisciplinary collaborations.
Keyphrases
  • human health
  • mental health
  • genome wide
  • risk assessment
  • life cycle