The effect of levodopa treatment on vascular endothelial function in Parkinson's disease.

Min Seung KimDon Gueu ParkYoung Eun GilIn Ja ShinJung Han Yoon

Published in: Journal of neurology (2023)

We found that 1-year levodopa treatment may adversely affect vascular endothelial function in de novo PD. Further studies are needed to clarify the exact pathogenesis and clinical implication of levodopa-induced endothelial dysfunction in PD.

Keyphrases

parkinson disease
deep brain stimulation
combination therapy
density functional theory
molecular dynamics
replacement therapy