Characterization of Cyclic N-Acyliminium Ions by Infrared Ion Spectroscopy.
Jona MerxKas J HouthuijsHidde ElferinkEva WitloxJasmin MecinovićJos OomensJonathan K MartensThomas J BoltjeFloris P J T RutjesPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2021)
N-Acyliminium ions are highly reactive intermediates that are important for creating CC-bonds adjacent to nitrogen atoms. Here we report the characterization of cyclic N-acyliminium ions in the gas phase, generated by collision induced dissociation tandem mass spectrometry followed by infrared ion spectroscopy using the FELIX infrared free electron laser. Comparison of DFT calculated spectra with the experimentally observed IR spectra provided valuable insights in the conformations of the N-acyliminium ions.
Keyphrases
- tandem mass spectrometry
- quantum dots
- high resolution
- aqueous solution
- density functional theory
- ultra high performance liquid chromatography
- high performance liquid chromatography
- liquid chromatography
- water soluble
- single molecule
- simultaneous determination
- gas chromatography
- mass spectrometry
- high glucose
- diabetic rats
- solid phase extraction
- endothelial cells