Elucidation of the molecular mechanism underlying the anti-inflammatory activity of an effective and safe bipyrazole-based compound.
Souraya A DomiatiM MehannaH RagabK H Abd El GalilH Nakkash-ChmaisseA El MallahPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2019)
These findings revealed the superiority of the newly synthesized bipyrazole compound not only on the binding site, but also by inhibiting most of the inflammatory mediators including TNF-α.