The impact of lesional inflammatory cellular infiltrate on the phenotype of bullous pemphigoid.

Sascha StänderC M HammersA VorobyevEnno SchmidtD ZillikensS GhorbanalipoorK BieberR J LudwigKhalaf Kridin

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2021)

Eosinophil-predominance and high cellularity in the lesional inflammatory infiltrate of BP skin are associated with increased seropositivity of anti-BP180 NC16A IgG. Lymphocyte-predominant infiltrates predict a more severe phenotype, pointing towards a pathogenic role of autoreactive lymphocytes.

Keyphrases

peripheral blood
oxidative stress
early onset
soft tissue
wound healing