Predictors of Disease-Free and Overall Survival in Retroperitoneal Sarcomas: A Modern 16-Year Multi-Institutional Study from the United States Sarcoma Collaboration (USSC).
Patrick B SchwartzKara Vande WalleEmily R WinslowCecilia G EthunThuy B TranGeorge PoultsidesJennifer TsengKevin RogginValerie GrignolJohn Harrison HowardBradley A KrasnickRyan C FieldsHarveshp MogalCallisia N ClarkeRebecca SenehiKonstantinos VotanopoulosKenneth CardonaDaniel E AbbottPublished in: Sarcoma (2019)
The strongest predictors of disease-free and overall survival are tumor-specific characteristics, while surgical factors are less impactful. Nonsurgical therapies are not associated with improved outcomes despite persistent interest and utilization. Complete macroscopic resection (R0/R1) remains a persistent potentially modifiable risk factor associated with improved overall survival in patients with retroperitoneal sarcomas.