Characterization of global 5-hydroxymethylcytosine in pediatric posterior fossa ependymoma.

Tao WuZhi-Wei ZhangShiwei LiBo WangZhijun YangPeng LiJing ZhangWei-Min TongChunde LiFu ZhaoYamei NiuPi-Nan Liu

Published in: Clinical epigenetics (2020)

Our findings suggest that loss of 5hmC is an epigenetic hallmark for pediatric posterior fossa ependymoma. 5hmC levels may represent a potential biomarker to predict prognosis in children with posterior fossa ependymoma.

Keyphrases

dna methylation
young adults
gene expression