Proton Pump Inhibitor Exposure and Acute Myocardial Infarction Risk: A Nested Cohort Study.
Hsiang-Jung TsengChih-Ming ChengShih-Jen TsaiWei-Chen LinYa-Mei BaiChia-Fen TsaiTung-Ping SuCheng-Ta LiTzeng-Ji ChenMu-Hong ChenPublished in: Cardiovascular toxicology (2021)
Our study demonstrated long-term or high-dose PPI exposure associated with increased new-onset AMI risk in patients without a history of any ischemic heart disease. The underlying mechanisms of PPI-related cardiovascular effects deserve more investigation.
Keyphrases
- acute myocardial infarction
- high dose
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- percutaneous coronary intervention
- low dose
- protein protein
- prognostic factors
- heart failure
- stem cell transplantation
- acute coronary syndrome
- small molecule
- atrial fibrillation
- case control
- breast cancer risk