Non-invasive hemodynamic profile of early COVID-19 infection.
Mattia BusanaMarco SchiavoneAntonio LanfranchiGiovanni Battista ForleoElisa CerianiChiara Beatrice CogliatiAlessio GasperettiPublished in: Physiological reports (2020)
In the early stages of COVID-19 infection the hemodynamic profile is characterized by a hyperdynamic circulatory state with high CI and low SVRI, while the right heart is functionally unaffected. Our findings suggest that hypoxemia, viral sepsis or peripheral shunting are possible mechanisms for the vasodilation that dominates at this stage of the disease and may itself worsen the gas exchange.