Evaluation of the reproducibility of responses to nasal allergen challenge and effects of inhaled nasal corticosteroids.

Rebecca N BauerYanqing XieSuzanne BeaudinLesley WiltshireJennifer WattieCaroline MuñozNadia AlsajiJohn Paul OliveriaXiaotian JuJonathan MacLeanDoron D SommerPaul K KeithImran SatiaRuth P CusackPaul M O'ByrneGizette SperindeMartha HokomOlga LiPrajna BanerjeeChen ChenTracy StatonRoma SehmiGail M Gauvreau

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2023)

NAC-induced biomarkers and symptoms are reproducible and responsive to INCS. NAC is suitable for assessing pharmacodynamic activity and proof of mechanism for drugs targeting allergic inflammation.

Keyphrases

transcription factor
cancer therapy
chronic rhinosinusitis
oxidative stress
allergic rhinitis
diabetic rats
high glucose
drug induced
cystic fibrosis
genome wide analysis
endothelial cells
atopic dermatitis