Baseline [ 18 F]FDG PET features are associated with survival and toxicity in patients treated with CAR T cells for large B cell lymphoma.
Etienne MarchalX Palard-NovelloF LhommeM E MeyerG MansonA DevillersJ P MarolleauR HouotA GirardPublished in: European journal of nuclear medicine and molecular imaging (2023)
TMTV and sDmax had independent prognostic values, respectively, on PFS and OS. Regarding adverse events, the mean liver and spleen uptakes were associated with the occurrence of grade 2 to 4 CRS and ICANS, respectively. Integrating these biomarkers into the clinical workflow could be useful for early adaptation of patients management.