Age-dependent favorable visual recovery despite significant retinal atrophy in pediatric MOGAD: how much retina do you really need to see well?

Joachim HavlaThivya PakeerathanCarolin SchwakeJeffrey L BennettIngo KleiterAna Felipe-RuciánStephanie C JoachimAmelie S Lotz-HavlaTania KümpfelMarkus KrumbholzEva M WendelMarkus ReindlCharlotte ThielsThomas LückeKerstin HellwigRalf GoldKevin RostasyIlya Ayzenberg

Published in: Journal of neuroinflammation (2021)

Pediatric MOGAD ON showed better visual recovery than adult MOGAD ON despite profound and almost identical neuroaxonal retinal atrophy. Age-related cortical neuroplasticity may account for the substantial discrepancy between structural changes and functional outcomes.

Keyphrases

diabetic retinopathy
optic nerve
optical coherence tomography
childhood cancer
intellectual disability
young adults
autism spectrum disorder