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Vaccination Ameliorates Cellular Inflammatory Responses in SARS-CoV-2 Breakthrough Infections.

Julio A HuapayaJeanette HigginsShreya KanthCumhur DemirkaleSalina GairheEtsubdink A AboyeDavid RegenoldS J SahagunGloria PastorDoris SwaimRobin DewarTauseef RehmanHelene C HighbargerPerrine LallemandSylvain LaverdureJoseph AdelsbergerAdam RupertWilly LiJanell KrackGebeyehu TeferiJanaki KuruppuJeffrey R StrichRichard DaveyRichard ChildsDaniel ChertowJoseph A KovacsChristopher BarnettParizad Torabi-PariziAnthony F Suffredininull null
Published in: The Journal of infectious diseases (2023)
Patients with SARS-CoV-2 breakthrough infections exhibit cellular immune responses that limit the progression of inflammatory responses and suggest mechanisms by which vaccination limits disease severity. These data may have implications for developing more effective vaccines and therapies.
Keyphrases
  • sars cov
  • immune response
  • respiratory syndrome coronavirus
  • electronic health record
  • mouse model
  • toll like receptor
  • dendritic cells
  • big data
  • machine learning
  • data analysis
  • inflammatory response
  • deep learning