APOE genotype influences P3b amplitude and response to smoking abstinence in young adults.
Ryan CoppensNorka E RabinovichRaghuveer KannegantiHerman A DiggsKristin WiggsTravis HealeyJodi HuggenvikGregory M RoseDavid G GilbertPublished in: Psychopharmacology (2021)
The results suggest that subjects with the APOE ε4 allele are more sensitive to nicotine, which could influence smoking patterns, the risk for nicotine dependence, and the cognitive effects of nicotine use in these individuals.