Composite outcomes in observational studies of ulcerative colitis: A systematic review and meta-analysis.

Fernando MagroCatarina AlvesMafalda SantiagoPaula MinistroPaula LagoLuís CorreiaRaquel GonçalvesDiana CarvalhoFrancisco PortelaCláudia Camila DiasAxel DignassSilvio DaneseLaurent Peyrin-BirouletMaria Manuela EstevinhoPaula Moreiranull null

Published in: United European gastroenterology journal (2021)

The frequency of composite outcomes in observational studies of UC is dependent on the specific identity of the variables being reported. Moreover, longer follow-up periods are associated with higher frequencies of composite outcomes. The evidence provided here is useful for the design of future observational studies of UC that aim to maximize the frequency of patients that achieve composite outcomes.

Keyphrases

ulcerative colitis
newly diagnosed
ejection fraction
type diabetes
metabolic syndrome
adipose tissue
glycemic control
patient reported