Biophysical properties of microvascular endothelium: Requirements for initiating and conducting electrical signals.
Adam KapelaErik J BehringerSteven S SegalNikolaos M TsoukiasPublished in: Microcirculation (New York, N.Y. : 1994) (2018)
High Rm makes the endothelium sensitive to electrical stimuli and able to conduct these signals effectively. Whereas the activation of a group of ECs is required to initiate physiologically relevant hyperpolarization, this requirement is increased by myoendothelial coupling and KCa activation along the endothelium inhibits conduction by dissipating electrical signals.
Keyphrases