Bio-Nanohybrid Gelatin/Quantum Dots for Cellular Imaging and Biosensing Applications.
Sangram Keshari SamalStefaan J SoenenDario PuppiKarolien De WaelSanghamitra PatiStefaan De SmedtKevin BraeckmansPeter DubruelPublished in: International journal of molecular sciences (2022)
The bio-nanohybrid gelatin protein/cadmium sulfide (Gel/CdS) quantum dots (QDs) have been designed via a facile one-pot strategy. The amino acids group of gelatin chelate Cd 2+ and grow CdS QDs without any agglomeration. The 1 H NMR spectra indicate that during the above process there are no alterations of the gelatin protein structure conformation and chemical functionalities. The prepared Gel/CdS QDs were characterized and their potential as a system for cellular imaging and the electrochemical sensor for hydrogen peroxide (H 2 O 2 ) detection applications were investigated. The obtained results demonstrate that the developed Gel/CdS QDs system could offer a simple and convenient operating strategy both for the class of contrast agents for cell labeling and electrochemical sensors purposes.
Keyphrases
- quantum dots
- hyaluronic acid
- hydrogen peroxide
- high resolution
- amino acid
- label free
- sensitive detection
- bone regeneration
- gold nanoparticles
- tissue engineering
- magnetic resonance
- nitric oxide
- energy transfer
- protein protein
- reduced graphene oxide
- ionic liquid
- loop mediated isothermal amplification
- cell therapy
- binding protein
- risk assessment
- heavy metals
- small molecule
- magnetic resonance imaging
- molecular dynamics simulations
- mass spectrometry
- contrast enhanced
- real time pcr