Role of Estrogen and Its Receptors in Adipose Tissue Glucose Metabolism in Pre- and Postmenopausal Women.
Fozia Z AhmedPrasad G KambleSusanne HettyGiovanni FanniMilica VranicAssel SarsenbayevaRobin KristófiKristina AlmbyMaria K SvenssonMaria J PereiraJan W ErikssonPublished in: The Journal of clinical endocrinology and metabolism (2022)
E2 inhibits glucose utilization in human adipocytes in late postmenopausal women. Changes in glucose utilization over time since menopause may be explained by a lower ESR1:ESR2 ratio. This can have clinical implications on the timing of estrogen treatment in postmenopausal women.