Piperlongumine inhibits diethylnitrosamine induced hepatocellular carcinoma in rats.

Ashish Kumar Manisha NaithaniNitesh KumarNeha SinghShruti AgrawalAmbika SharmaSurabhi ThapliyalJagjit SinghShailendra Handu

Published in: Human & experimental toxicology (2022)

The potential chemopreventive actions of piperlongumine may be due to its free radical scavenging and antiproliferative effect. Therefore, piperlongumine may serve as a novel therapeutic agent for the treatment of hepatocellular carcinoma.

Keyphrases

high glucose
diabetic rats
drug induced
risk assessment
oxidative stress
human health
replacement therapy