SARS-CoV-2 Serosurveys: How antigen, isotype and threshold choices affect the outcome.

Raquel A BinderGavin F FujimoriCatherine S ForconiGeorge W ReedLeandro S SilvaPriya Saikumar LakshmiAmanda HigginsLindsey CincottaProtiva DuttaMarie-Claire SaliveVirginia MangoldsOtuwe AnyaJ Mauricio Calvo CalleThomas NixonQiushi TangMireya WessolosskyYang WangDominic A RitaccoCourtney S BlyStephanie FischingerCaroline AtyeoPeter O OluochBoaz OdwarJeffrey A BaileyAna Maldonado-ContrerasJohn P HaranAaron G SchmidtLisa CavaciniGalit AlterAnn M Moormann

Published in: The Journal of infectious diseases (2022)

This study revealed the importance of evaluating serosurvey tools for antigen, isotype, and threshold-specific sensitivity and specificity, in order to interpret qualitative serosurvey outcomes reliably and consistently across studies.

Keyphrases

sars cov
systematic review
respiratory syndrome coronavirus
metabolic syndrome
skeletal muscle