Optimized method for normal range estimation of standardized uptake values (SUVmax, SUVmean) in liver SPECT/CT images with somatostatin analog [99mTc]-HYNIC-TOC (Tektrotyd).

Hanna Piwowarska-Bilska Hanna Piwowarska-Bilska Bozena Birkenfeld

Published in: Nuclear medicine review. Central & Eastern Europe (2022)

Segmentation in the mid-coronal computed tomography (CT) image, at one-fourth of the height of the liver measured from the top, with a medium-sized volume of interest (VOI) outlined on a given transverse SPECT slice was regarded as the optimal method for estimating normal ranges for standardized uptake values. It is necessary to standardize quantification methods in the SPECT/CT studies. Our work is a step forward in obtaining standardization of SPECT/CT SUV calculation methods. Calculations for radiopharmaceutical uptake in tumors with volumes smaller than 5 mL are biased with a significant measurement error.

Keyphrases

computed tomography
image quality
dual energy
contrast enhanced
positron emission tomography
pet ct
deep learning
magnetic resonance imaging
convolutional neural network
body mass index
machine learning
magnetic resonance
optical coherence tomography
density functional theory