Cardioprotective Natural Compound Pinocembrin Attenuates Acute Ischemic Myocardial Injury via Enhancing Glycolysis.

Yanjun ZhengGuoqing WanBo YangXuefeng Gu Jing-Rong Lin

Published in: Oxidative medicine and cellular longevity (2020)

In conclusion, these results established that the acute cardioprotective benefits of pinocembrin are mediated in part via enhancing PFKFB3-mediated glycolysis via HIF1α, which may provide a new therapeutic target to impede the progression of myocardial I/R injury.

Keyphrases

liver failure
respiratory failure
aortic dissection
drug induced
left ventricular
hepatitis b virus
heart failure
ischemia reperfusion injury
endothelial cells
intensive care unit
mechanical ventilation
cerebral ischemia