Loss of host tissue transglutaminase boosts antitumor T cell immunity by altering STAT1/STAT3 phosphorylation in ovarian cancer.
Livia Elena SimaSiqi ChenHoracio CardenasGuangyuan ZhaoYinu WangCristina IvanHao HuangBin ZhangDaniela MateiPublished in: Journal for immunotherapy of cancer (2022)
mice. We propose that TG2 acts as an attenuator of antitumor T cell immunity and is a new immunomodulatory target.